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KMID : 0358320070480080843
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Korean Journal of Urology
2007 Volume.48 No. 8 p.843 ~ p.848
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In Vitro Retrieval of Epididymal Sperm: An Analysis of 11 Years of Cumulative Data
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Kim Jin-Soo
Kim Sung-Jin
Han Hyuk-Dong
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Abstract
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Purpose: To evaluate the efficacy of in vitroretrieval of epididymal sperm for the induction of pregnancy in patients with post-testicular causes of infertility, and assess the sperm distribution within the epididymis of these patients.
Materials and Methods: Analyses of the sperm count and motility of sperm retrieved from the detached epididymis, and of the resulting fertilization and pregnancy outcomes were conducted. A total 62 infertile couples, due to post-testicular male causes, had sperm retrieved from the epididymis. The sperm count and motility, as well as the fertilization and pregnancy rates, were measured.
Results: Epididymal sperm was retrieved from 60 males with post-testicular infertility. The average sperm concentration and motility of the sperm after sperm preparation were 43.0x106/ml and 25%, respectively. The clinical pregnancy rate per cycle was 57.9%(11/19) with in vitro fertilization(IVF), 39.0%(16/41) with intracytoplasmic sperm injection(ICSI) using fresh epididymal sperm, and 42.9%(27/63) with ICSI using frozen epididymal sperm.
Conclusions: The in vitro retrieval of epididymal sperm is recommended as a simple and effective method to obtain viable sperm from infertile patients with obstructive azoospermia or sperm excretion disorders.
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KEYWORD
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Epididymal sperm retrieval, Male infertility, Azoospermia
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